<div class> <p><br/> 周亚军</strong>:男,1964年12月生,教授,生化药学与分子生物学研究生导师。1995年7月华东师范大学生物化学 与分子生物学专业研究生毕业,获理学硕士学位,2001年9月日本德岛大学内科学专业博士研究生毕业,获医学博士学位, 2005-2006年美国路易斯安娜州立大学高访、博士后。从事肝纤维化机制与防治基础研究10多年,近年来,先后主持承担国家、省厅级研究课题6项(其 中,国家自然科学基金面上项目2项),作为第一作者(或通讯作者)在MOLECULAR MEDICINE 等国内外权威杂志发表专业学术论文30多篇。</p> <p> 通讯作者(或第一作者)代表作: </strong><br/> <br/> 1、PI-3 K/AKT and ERK signaling pathways mediate leptin-induced inhibition of PPARgamma gene expression in primary rat hepatic stellate cells.Mol Cell Biochem. 2009;325(1-2):131-93.<br/> <br/> 2、Egr-1 is involved in the inhibitory effect of leptin on PPARgamma expression in hepatic stellate cell in vitro. Life Sci. 2009; 10;84(15-16):544-5514 <br/> <br/> 3、The interruption of the PDGF and EGF signaling pathways by curcumin stimulates gene expression of PPARgamma in rat activated hepatic stellate cell in vitro.Lab Invest. 2007;87(5):488-4985 <br/> <br/> 4、Leptin inhibits PPARgamma gene expression in hepatic stellate cells in the mouse model of liver damage. Mol Cell Endocrinol. 2010;29;323(2):193-200<br/> <br/> 5、p38 Mitogen-Activated Protein Kinase and Liver X Receptor-alpha Mediate the Leptin Effect on Sterol Regulatory Element Binding Protein-1c Expression in Hepatic Stellate Cells.MOLECULAR MEDICINE 2012,18(1):10-18<br/> <br/> 6、beta-Catenin pathway is required for TGF-beta 1 inhibition of PPAR gamma expression in cultured hepatic stellate cells. PHARMACOLOGICAL RESEARCH 2012,66(3):219-225<br/> <br/> 7、.Stat3 pathway correlates with the roles of leptin in mouse liver fibrosis and sterol regulatory element binding protein-1c expression of rat hepatic stellate cells Int J Biochem Cell Biol.. 2013 Mar;45(3):736-44.<br/> <br/> *如果发现导师信息存在错误或者偏差,欢迎随时与我们联系,以便进行更新完善。联系方式>></a></p> </div>